Apurinic/apyrimidinic endonuclease 1 (APE1) is the principal enzyme responsible for recognising and cleaving abasic sites—locations in DNA where bases have been lost due to spontaneous hydrolysis or ...

A team led by Professor Michal Hocek at IOCB Prague has explored the limits of the structure and function of DNA and successfully pushed forward known boundaries. Their latest research has just been ...

Picture in your mind a traditional "landline" telephone with a coiled cord connecting the handset to the phone. The coiled telephone cord and the DNA double helix that stores the genetic material in ...

DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study. DNA can mimic protein functions by folding into elaborate, three-dimensional ...

Researchers reveal how DNA gyrase resolves DNA entanglements. The findings not only provide novel insights into this fundamental biological mechanism but also have potential practical applications.

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...

Antibodies, also known as immunoglobulins, are specialized proteins that are generated by the immune system to identify and ...

Researchers from North Carolina State University and Johns Hopkins University have demonstrated a technology capable of a suite of data storage and computing functions – repeatedly storing, retrieving ...

Chromosomes are thread-like structures comprising DNA that are present inside the nucleus of every cell in the body. Specific segments of DNA are called genes. Every chromosome contains many genes, ...

Genes are specific segments of DNA that influence certain aspects of growth and health. Collectively, scientists refer to all of an organism’s genes as a genome. DNA is the genetic material or code ...