The discovery of catalytic RNA transformed our understanding of life’s beginnings. Clare Sansom explores how the RNA world hypothesis bridges the gap between non-living chemistry and the first cells ...

We are living in an era where biology has become synonymous with big data due to the ever-increasing amount of data being generated by technologies such as next-generation sequencing. Bioinformatics ...

Abstract: This research analyzes RNA sequencing data collected from individual cell data from the GSE127471 and GSE245170 datasets to identify potential biomarkers and treatment targets in non-small ...

Abstract: The CRISPR-Cas9 gene editing, based on a bacterial immune mechanism, offers precise DNA editing techniques for gene therapy, disease treatment, and improved agricultural crops. This paper ...

RNA editing is a post-transcriptional phenomenon involving the insertion/deletion or substitution of specific bases in precise RNA localizations. In humans, RNA editing occurs by deamination of ...

Single-cell multi-omics technologies allow a profound system-level biology understanding of cells and tissues. However, an integrative and possibly systems-based analysis capturing the different ...

Recent advancements in experimental and computational methods for RNA secondary structure detection have revealed the crucial role of RNA structural elements in diverse molecular processes within ...